Improve your energy levels today.
Are you constantly waking up feeling tired, yet facing another busy day at work? Do you survive on coffee, energy drinks or sugar laden foods to give you the energy to get through the day? Adrenal fatigue and chronic fatigue syndrome have both been linked to ongoing levels of chronic stress. Chronic stress, often from the pressures of work, finances, and family commitments can lead to high levels of burnout resulting in depression, anxiety and fatigue. The World Health Organisation (WHO) has classified stress as the “health epidemic of the 21st century.”
Fatigue is an extremely common condition and is most prevalent in females aged in their late 30’s to early 40s. It is the most common unexplained complaint presenting to GPs with just 4% of cases receiving a medical diagnosis after conventional lab testing. Worse still, 43% of cases are given a final diagnosis of ‘tiredness’1. Together with fatigue many people will experience depression and weight gain.
Fatigue is defined as “that state… characterised by a lessened capacity or motivation for work… usually accompanied by a feeling of weariness, sleepiness, irritability or loss of attention”
1. Acute, or short-lasting fatigue results from short term sleep loss, or resulting from brief periods of physical or mental exertion. The affects of acute fatigue are short-lived and can usually be reversed with sleep and relaxation. Chronic fatigue is an often-debilitating condition which lasts six months or longer.
If you’ve been struggling with chronic fatigue you may be suffering from increased job or emotional stress resulting in burnout which can be measured via our DUTCH testing procedure. The most characteristic component of burnout is emotional exhaustion, feeling as if you’re over extended, depleted of emotional and physical strength. Burnout is often due to adrenal fatigue and can show up as low cortisol, a blunted Cortisol Awakening Response (CAR) and depression
2.
Fatigue is often a symptom of other underlying conditions. Common causes of fatigue are;
- Nutrient deficiencies
- Fibromyalgia
- Adrenal Fatigue
- Thyroid problems
- Metabolic syndrome
- Mitochondrial dysfunction & Oxidative stress
- Hormonal imbalances like PMS
How we can help your underlying causes of fatigue;
1. Macro or micronutrient deficiencies
It has long been established that nutrient deficiencies can cause fatigue. Identifying these deficiencies and more importantly the cause of such deficiencies is key in designing a program to help you recover from chronic fatigue and regain normal energy levels. I often see people in clinic who rely on caffeine or sugar to get through the day. This can often make fatigue levels worse in the long term.
Whilst standard blood tests are a good place to start for measuring imbalances in micronutrients such as Iron, functional lab testing can dive deeper in identifying other causes of your fatigue.
2. Mitochondrial Dysfunction: Mitochondria and the energy they produce play an essential role in health and disease.
Organic acid testing (OAT) can identify disturbances in the functioning of the mitochondria via the excretion via urine of TCA cycle intermediates and other organic acids related to mitochondrial function
3. From your OAT, Dr Clegg can help you replace the necessary micronutrients to help restore mitochondrial function and regain normal energy levels
4-14. In addition to specific amino acids, vitamins and minerals, Dr. Clegg utilizes a novel Lipid Replacement Therapy (LRT) which due to its action on the mitochondrial membrane, has been shown to improve fatigue and aid in weight loss
12,15.
Mitochondrial dysfunction is caused by a number of factors including; Heavy metals and environmental toxins18,19, gut health20, viruses21 and household pollutants such as mycotoxins (mould)18.
Fibromyalgia is an often debilitating, painful disorder which affects around 5% of the population, predominately women. It’s been suggested in the literature that mitochondrial dysfunction and oxidative stress has a role to play in the aetiology of fibromyalgia.
If you suspect that your fatigue is related to mitochondrial dysfunction speak with Dr. Clegg to organise functional lab testing.
3. Adrenal Fatigue (HPA axis dysfunction)
The chronic stress response and subsequent imbalances in cortisol can be extremely damaging to your health, resulting in fatigue and other conditions such as;
- Anxiety
22- Decreased immunity which can result in infections and intestinal inflammation
23- Development of food sensitivities and allergies
24- Depression
25- Type II Diabetes
26- Weight gain
27- Fibromyalgia and Chronic Fatigue Syndrome
28
The Kalish Method of Functional Medicine and Clinical Nutrition as practiced by Dr Clegg can help you correct a dysfunctional HPA axis, improve your metabolic resilience and balance stress hormones such as cortisol
29-32.
It is important to determine which “stage” of Adrenal Fatigue you are in before any treatment protocols are established
2. To measure your Adrenal hormones Dr. Clegg prefers the DUTCH test as it provides a greater level of information than blood or saliva testing
33-36.
4. Thyroid problems
An underactive thyroid can often cause fatigue and has been associated with conditions such as fibromyalgia
8. Hypothyroidism has been linked to cortisol and adrenal dysfunction
37. Hashimoto’s thyroiditis, the most common cause of an underactive thyroid is a type of autoimmune disorder. The root cause of which has been linked to increased intestinal permeability.
REFERENCES
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15. Lipid Replacement Therapy Functional Food Formulation with NT Factor for Reducing Weight, Girth, Body Mass, Appetite and Fatigue While Improving Blood Lipid Profiles.pdf
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19. Meyer, J.N et al. (2013) Mitochondria as a Target of Environmental Toxicants.
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